ea0021oc2.4 | Neuroendocrine tumours/pituitary | SFEBES2009
Ozfirat Zehra
, Cain Josh
, Chahal Harvinder
, Stals Karen
, Ellard Sian
, Howlett Trevor
, Levy Miles
, Atkinson Brew
, Morrison Patrick
, Akker Scott
, Grossman Ashley
, Korbonits Marta
Mutations in the co-chaperone molecule AIP account for a predisposition to pituitary tumours in some families with familial isolated pituitary adenomas (FIPA). We now report on four apparently-unrelated families with the same mutation and originating from the same geographical area, suggesting a possible founder mutation.The index patient had gigantism (19 years, 208 cm) and had a female 4th cousin, once removed (13 years, 191 cm) with a large pituitary ...